Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001637)
Formula
SVG example
Oxidation
Reactant Megestrol acetate Product Megestrol acetate metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001636 Megestrol acetate Megestrol acetate metabolite M1 Oxidation - Oxidation Megestrol acetate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001635 Megestrol acetate metabolite M2 Megestrol acetate metabolite MG2 Conjugation - Glucuronidation Megestrol acetate [1]
References
1 Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct;48(10):973-983.

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