Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001762)
Formula Reactant Nitrofurantoin metabolite M10 Product Nitrofurantoin metabolite 8(M1/M2)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2A6 (CYP2A6) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001764 Nitrofurantoin Nitrofurantoin metabolite M10 Oxidation - Oxidation Nitrofurantoin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001763 Nitrofurantoin metabolite M10 Nitrofurantoin metabolite 9(M1/M2) Oxidation - Oxidation Nitrofurantoin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001765 Nitrofurantoin Nitrofurantoin metabolite 8(M1/M2) Oxidation - Oxidation Nitrofurantoin [1]
References
1 Oxidative bioactivation of nitrofurantoin in rat liver microsomes Xenobiotica. 2017 Feb;47(2):103-111. doi: 10.3109/00498254.2016.1164913.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.