Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001797)
Formula Reactant 9-Aminocamptothecin metabolite M2 Product 9-Aminocamptothecin metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001798 NSC-603071 9-Aminocamptothecin metabolite M2 Unclear NSC-603071 [1]
References
1 Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: impact on cancer therapy. Int J Oncol. 2014 Aug;45(2):877-86.

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