Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001798)
Formula Reactant NSC-603071 Product 9-Aminocamptothecin metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001797 9-Aminocamptothecin metabolite M2 9-Aminocamptothecin metabolite M1 Unclear NSC-603071 [1]
References
1 Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: impact on cancer therapy. Int J Oncol. 2014 Aug;45(2):877-86.

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