Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001843)
Formula
CYP3A4 ...
SVG example
Reactant Org-33062 Product 3'-OH-gepirone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001842 Org-33062 1-Pyrimidinylpiperazine Unclear Org-33062 [1]
MR001845 Org-33062 2-OH-gepirone Unclear Org-33062 [1]
MR001844 Org-33062 5-OH-gepirone Unclear Org-33062 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012624 Gepirone 3-Hydroxygepirone Unclear - Unclear Gepirone [2]
References
1 Human cytochromes mediating gepirone biotransformation at low substrate concentrations. Biopharm Drug Dispos. 2003 Mar;24(2):87-94.
2 PubChem:Gepirone

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.