Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002025)
Formula
CYP2C9 ...
SVG example
4'-Hydroxylation
Reactant Phenprocoumon Product 4'-hydroxy-R-phenprocoumon
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - 4'-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002026 Phenprocoumon 6-hydroxy-R-phenprocoumon Oxidation - 6-Hydroxylation Phenprocoumon [1]
MR002028 Phenprocoumon 7-hydroxy-R-phenprocoumon Oxidation - 7-Hydroxylation Phenprocoumon [1]
MR002027 Phenprocoumon 8-hydroxy-R-phenprocoumon Oxidation - 8-Hydroxylation Phenprocoumon [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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