Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002026)
Formula
CYP2C9 ...
SVG example
6-Hydroxylation
Reactant Phenprocoumon Product 6-hydroxy-R-phenprocoumon
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - 6-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002025 Phenprocoumon 4'-hydroxy-R-phenprocoumon Oxidation - 4'-Hydroxylation Phenprocoumon [1]
MR002028 Phenprocoumon 7-hydroxy-R-phenprocoumon Oxidation - 7-Hydroxylation Phenprocoumon [1]
MR002027 Phenprocoumon 8-hydroxy-R-phenprocoumon Oxidation - 8-Hydroxylation Phenprocoumon [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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