Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR002221)
Formula	CYP3A4 ... Hydroxylation
	Reactant	Salmeterol xinafoate		Product	Alpha-hydroxysalmeterol
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
	Cytochrome P450 3A5 (CYP3A5)					DME Info
	Cytochrome P450 3A7 (CYP3A7)					DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002222	Salmeterol xinafoate	Salmeterol O-dealkylated metabolite	Oxidation - O-Dealkylation	Salmeterol xinafoate	[1]

References
1	Disposition of salmeterol xinafoate in laboratory animals and humans Drug Metab Dispos. 1993 Nov-Dec;21(6):1022-8.

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