Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002237)
Formula Reactant ACT-333679 Product Hydroxylated and dealkylated products
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002239 Selexipag ACT-333679 Hydrolysis - Hydrolysis Selexipag [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002238 ACT-333679 ME9Qgl9thj Conjugation - Glucuronidation Selexipag [1]
References
1 FDA LABEL:elexipag

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.