Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002341)
Formula
SVG example
Hydroxylation
Reactant Tasimelteon Product Tasimelteon metabolite M14
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002342 Tasimelteon Inosine Oxidation - Hydroxylation Tasimelteon [1]
MR002340 Tasimelteon Tasimelteon metabolite M13 Oxidation - Hydroxylation Tasimelteon [1]
References
1 Clinical assessment of drug-drug interactions of tasimelteon, a novel dual melatonin receptor agonist. J Clin Pharmacol. 2015 Sep;55(9):1004-11.

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