Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002340)
Formula Reactant Tasimelteon Product Tasimelteon metabolite M13
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002342 Tasimelteon Inosine Oxidation - Hydroxylation Tasimelteon [1]
MR002341 Tasimelteon Tasimelteon metabolite M14 Oxidation - Hydroxylation Tasimelteon [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002339 Tasimelteon metabolite M13 Tasimelteon metabolite M11 Unclear Tasimelteon [1]
MR002338 Tasimelteon metabolite M13 Tasimelteon metabolite M9 Unclear Tasimelteon [1]
References
1 Clinical assessment of drug-drug interactions of tasimelteon, a novel dual melatonin receptor agonist. J Clin Pharmacol. 2015 Sep;55(9):1004-11.

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