Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002343)
Formula Reactant Tazarotenic acid Product AGN 190844
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Flavin-containing monooxygenase (FMO) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002348 Tazarotene Tazarotenic acid Hydrolysis - Hydrolysis Tazarotene [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002345 AGN 190832 AGN 190844 Hydrolysis - Hydrolysis Tazarotene [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002344 AGN 190844 AGN 190843 Oxidation - Oxidation Tazarotene [1]
References
1 Clinical pharmacokinetics and drug metabolism of tazarotene: a novel topical treatment for acne and psoriasis Clin Pharmacokinet. 1999 Oct;37(4):273-87. doi: 10.2165/00003088-199937040-00001.

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