Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002451)
Formula
SVG example
Hydroxylation
Reactant Triamterene Product 4'-OH-triamterene
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002450 4'-OH-triamterene 4'-OH-triamterene sulfate metabolite Conjugation - Sulfation Triamterene [1], [2]
References
1 Pharmacokinetics of triamterene and its metabolite in man J Pharmacokinet Biopharm. 1982 Oct;10(5):507-23. doi: 10.1007/BF01059034.
2 Pharmacokinetics of triamterene Clin Exp Hypertens A. 1983;5(2):249-69. doi: 10.3109/10641968309048825.

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