Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002552)
Formula Reactant Brivaracetam Product Brivaracetam metabolite M1b
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002548 Brivaracetam Brivaracetam metabolite M1a Unclear Brivaracetam [1]
MR002547 Brivaracetam Brivaracetam metabolite M2 Unclear Brivaracetam [1]
MR002556 Brivaracetam Brivaracetam metabolite M9 Hydrolysis - Hydrolysis Brivaracetam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002553 Brivaracetam metabolite M1b Brivaracetam metabolite M3 Unclear Brivaracetam [1]
MR002554 Brivaracetam metabolite M1b Brivaracetam metabolite M4b Unclear Brivaracetam [1]
References
1 Pharmacokinetics and metabolism of 14C-brivaracetam, a novel SV2A ligand, in healthy subjects. Drug Metab Dispos. 2008 Jan;36(1):36-45.

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