Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002738)
Formula
SVG example
Reactant Etodolac Product 4-ureido-etodolac
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002735 Etodolac 6-hydroxyetodolac Oxidation - 6-Hydroxylation Etodolac [1]
MR002734 Etodolac 7-hydroxyetodolac Oxidation - 7-Hydroxylation Etodolac [1]
MR002736 Etodolac 8-(1-hydroxyethyl)etodolac Oxidation - Hydroxylation Etodolac [2]
MR002737 Etodolac Etodolac acyl glucuronide Conjugation - Glucuronidation Etodolac [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development Curr Med Chem. 2009;16(27):3480-675. doi: 10.2174/092986709789057635.
2 Etodolac clinical pharmacokinetics

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