Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002785)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant 2-Oxoquazepam Product 3-hydroxy-2-oxoquazepam
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002788 Quazepam 2-Oxoquazepam Hydrolysis - Hydrolysis Quazepam [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002786 2-Oxoquazepam N-Desalkyl-2-oxoquazepam Unclear Quazepam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002787 3-hydroxy-2-oxoquazepam 3-hydroxy-2-oxoquazepam glucuronide Conjugation - Glucuronidation Quazepam [1]
References
1 In vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions. Xenobiotica. 2004 Nov-Dec;34(11-12):1001-11.

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