Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR002788)
Formula	CYP3A4 ... Hydrolysis
	Reactant	Quazepam		Product	2-Oxoquazepam
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
	Cytochrome P450 2C9 (CYP2C9)					DME Info
	Mephenytoin 4-hydroxylase (CYP2C19)					DME Info
Metabolic Type	Hydrolysis - Hydrolysis

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002785	2-Oxoquazepam	3-hydroxy-2-oxoquazepam	Oxidation - Hydroxylation	Quazepam	[1]
MR002786	2-Oxoquazepam	N-Desalkyl-2-oxoquazepam	Unclear	Quazepam	[1]

References
1	In vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions. Xenobiotica. 2004 Nov-Dec;34(11-12):1001-11.

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