Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002786)
Formula
CYP3A4 ...
SVG example
Reactant 2-Oxoquazepam Product N-Desalkyl-2-oxoquazepam
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002788 Quazepam 2-Oxoquazepam Hydrolysis - Hydrolysis Quazepam [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002785 2-Oxoquazepam 3-hydroxy-2-oxoquazepam Oxidation - Hydroxylation Quazepam [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005039 Flurazepam N-desalkyl flurazepam Unclear Flurazepam [2]
MR005038 Flurazepam Metabolite N-desalkyl flurazepam Unclear Flurazepam [2]
MR005037 Flurazepam Metabolite-DE N-desalkyl flurazepam Unclear Flurazepam [2]
MR005035 Flurazepam Metabolite N-desalkyl flurazepam Unclear Flurazepam [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005036 N-desalkyl flurazepam Flurazepam Metabolite Unclear Flurazepam [2]
References
1 In vitro metabolism of quazepam in human liver and intestine and assessment of drug interactions. Xenobiotica. 2004 Nov-Dec;34(11-12):1001-11.
2 Metabolism of flurazepam, a benzodiazepine, in man and dog

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