| General Information of This Metabolic Reaction (MR) (ID:
MR002843) |
| Formula |
|
| Reactant |
Dydrogesterone |
Product |
20alpha-dihydroxydydrogesterone |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 3A4 (CYP3A4)
|
DME Info
|
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
|
|
Aldo-keto reductase 1C2 (AKR1C2)
|
DME Info
|
|
Aldo-keto reductase 1C1 (AKR1C1)
|
DME Info
|
|
Aldo-keto reductase 1C3 (AKR1C3)
|
DME Info
|
|
Metabolic Type
|
Oxidation
-
Hydroxylation
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
|
|
|
| References |
| 1 |
Dydrogesterone metabolism in human liver by aldo-keto reductases and cytochrome P450 enzymes Xenobiotica. 2016 Oct;46(10):868-74. doi: 10.3109/00498254.2015.1134852.
|
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