Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002844)
Formula
SVG example
Reactant Dydrogesterone Product 16alpha-hydroxyprogesterone
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002843 Dydrogesterone 20alpha-dihydroxydydrogesterone Oxidation - Hydroxylation Dydrogesterone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002170 Progesterone 16alpha-hydroxyprogesterone Oxidation - Hydroxylation Progesterone [2]
References
1 Dydrogesterone metabolism in human liver by aldo-keto reductases and cytochrome P450 enzymes Xenobiotica. 2016 Oct;46(10):868-74. doi: 10.3109/00498254.2015.1134852.
2 Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes. Arch Biochem Biophys. 1997 Oct 1;346(1):161-9.

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