Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003078)
Formula
SVG example
Reactant Agmatine Product Urea
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003072 Agmatine Gamma-guanidinobutyraldehyde Unclear Agmatine [1]
MR003079 Agmatine H2O2 Unclear Agmatine [1]
MR003066 Agmatine Putrescine Unclear Agmatine [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000203 Ammonia Urea Unclear Ammonia [4]
MR004282 [1-(2-aminoimidazol-1-yl)-3-methoxypropan-2-ol] (AIM) Urea Hydrolysis - Hydrolyzation Misonidazole [5]
MR003075 Gamma-guanidinobutyrate Urea Unclear Agmatine [1], [6]
MR004034 Allantoic acid Urea Unclear Xanthine [7]
MR005276 FUPA Urea Hydrolysis - Hydrolysis Tegafur-uracil [8]
References
1 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
2 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
3 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.
4 Ammonia Transporters and Their Role in Acid-Base Balance Physiol Rev. 2017 Apr;97(2):465-494. doi: 10.1152/physrev.00011.2016.
5 Comparative misonidazole metabolism in anaerobic bacteria and hypoxic Chinese hamster lung fibroblast (V-79-473) cells
6 A guanidine-degrading enzyme controls genomic stability of ethylene-producing cyanobacteria. Nat Commun. 2021 Aug 26;12(1):5150. doi: 10.1038/s41467-021-25369-x.
7 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
8 DrugBank(Pharmacology-Metabolism):Tegafur-uracil

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