Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003318)
Formula
SVG example
Reactant 4-hydroxynimesulideM1 Product Nimesulide metabolite M5A,5B
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003328 Nimesulide 4-hydroxynimesulideM1 Unclear Nimesulide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003319 4-hydroxynimesulideM1 Nimesulide metabolite M2 Unclear Nimesulide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003320 Nimesulide metabolite M5A,5B Nimesulide metabolite M2 Unclear Nimesulide [1]
MR003323 Nimesulide metabolite M5A,5B Nimesulide metabolite M5C Unclear Nimesulide [1]
MR003322 Nimesulide metabolite M5A,5B Nimesulide metabolite M7 Unclear Nimesulide [1]
MR003324 Nimesulide metabolite M5A,5B Nimesulide metabolite M8 Unclear Nimesulide [1]
MR003321 Nimesulide metabolite M5A,5B Nimesulide metabolite M9 Unclear Nimesulide [1]
References
1 Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: evidence for bioactivation Chem Res Toxicol. 2010 Nov 15;23(11):1691-700. doi: 10.1021/tx1001496.

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