Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003686)
Formula
CYP3A5 ...
SVG example
Reactant KW-5338 Product 5-hydroxydomperidone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003687 KW-5338 KW-5338 Metabolite M1 Oxidation - Hydrolyzationn KW-5338 [1]
MR003691 KW-5338 KW-5338 Metabolite M2 Oxidation - Hydrolyzationn KW-5338 [1]
MR003688 KW-5338 KW-5338 Metabolite M3 Oxidation - Hydrolyzationn KW-5338 [1]
MR003689 KW-5338 KW-5338 Metabolite M4 Oxidation - Hydrolyzationn KW-5338 [1]
MR003690 KW-5338 KW-5338 Metabolite M5 Oxidation - Hydrolyzationn KW-5338 [1]
References
1 Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone. Xenobiotica. 2004 Nov-Dec;34(11-12):1013-23.

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