Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003783)
Formula Reactant NE-10064 Product NE-10064 Metabolite M4
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Flavin-containing monooxygenase (FMO) DME Info
Metabolic Type Oxidation - N-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003788 NE-10064 NE-10064 Metabolite M1 Unclear NE-10064 [1]
MR003784 NE-10064 NE-10064 Metabolite M2 Unclear NE-10064 [1]
MR003786 NE-10064 NE-10064 Metabolite M3 Unclear NE-10064 [1]
MR003787 NE-10064 NE-10064 Metabolite M5 Unclear NE-10064 [1]
MR003785 NE-10064 NE-10064 Metabolite M6 Unclear NE-10064 [1]
References
1 The metabolic profile of azimilide in man: in vivo and in vitro evaluations. J Pharm Sci. 2005 Sep;94(9):2084-95.

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