Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003787)
Formula Reactant NE-10064 Product NE-10064 Metabolite M5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003788 NE-10064 NE-10064 Metabolite M1 Unclear NE-10064 [1]
MR003784 NE-10064 NE-10064 Metabolite M2 Unclear NE-10064 [1]
MR003786 NE-10064 NE-10064 Metabolite M3 Unclear NE-10064 [1]
MR003783 NE-10064 NE-10064 Metabolite M4 Oxidation - N-oxidation NE-10064 [1]
MR003785 NE-10064 NE-10064 Metabolite M6 Unclear NE-10064 [1]
References
1 The metabolic profile of azimilide in man: in vivo and in vitro evaluations. J Pharm Sci. 2005 Sep;94(9):2084-95.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.