Details of the Metabolic Reaction (MR)
General Information of This Metabolic Reaction (MR) (ID: MR003985) | ||||||
---|---|---|---|---|---|---|
Formula |
PNP
...
Hydrolysis
|
|||||
Reactant | SRT-647 | Product | Nicotinamide (NAM) | |||
Reactant Info | Product Info | |||||
Metabolic Enzyme | Purine nucleoside phosphorylase (PNP) | DME Info | ||||
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (BST1) | DME Info | |||||
Metabolic Type | Hydrolysis - Hydrolysis | |||||
References | ||||||
---|---|---|---|---|---|---|
1 | Pharmacokinetics of nicorandil | |||||
2 | Effects of formulation design on niacin therapeutics: mechanism of action, metabolism, and drug delivery | |||||
3 | #NAME? | |||||
4 | Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. J Biol Chem. 2003 Mar 28;278(13):10914-21. | |||||
5 | Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism | |||||
6 | BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities |
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.