Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004026)
Formula
SVG example
Reactant GMP Product IMP
Reactant Info Product Info
Metabolic Enzyme GMP reductase (guaC) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004025 XMP GMP Unclear Xanthine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004030 GMP GTP Unclear Xanthine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000082 Adenosine phosphate Adenosine phosphate metabolite IMP Unclear Adenosine phosphate [2], [3]
MR007514 Inosine IMP Unclear Inosine [4], [5]
MR011568 ZMP IMP Unclear - Unclear Acadesine [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000081 Adenosine phosphate metabolite IMP Inosine Unclear Adenosine phosphate [2], [3]
MR011569 IMP AMP Unclear - Unclear Acadesine [6]
MR004027 IMP SAMP Unclear Xanthine [1]
References
1 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
2 Condition-dependent adenosine monophosphate decomposition pathways in striated adductor muscle from Japanese scallop (Patinopecten yessoensis) J Food Sci. 2020 May;85(5):1462-1469. doi: 10.1111/1750-3841.15142.
3 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
4 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
5 Inosine in Biology and Disease
6 A multi-centre dose-escalation and pharmacokinetic study of diflomotecan in patients with advanced malignancy

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