Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011569)
Formula
SVG example
Unclear
Reactant IMP Product AMP
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000082 Adenosine phosphate Adenosine phosphate metabolite IMP Unclear Adenosine phosphate [1], [2]
MR007514 Inosine IMP Unclear Inosine [3], [4]
MR011568 ZMP IMP Unclear - Unclear Acadesine [5]
MR004026 GMP IMP Unclear Xanthine [6]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000081 Adenosine phosphate metabolite IMP Inosine Unclear Adenosine phosphate [1], [2]
MR004027 IMP SAMP Unclear Xanthine [6]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000076 Adenosine AMP Other reaction - Phosphorylation Adenosine [7], [2]
MR004265 Adenine AMP Unclear Methylthioadenosine [8]
MR011012 Adenosine diphosphate Adenosine Phosphate Unclear - Unclear Adenosine triphosphate [9]
MR000074 ATP AMP Other reaction - Dephosphorylation Adenosine [7], [2]
MR000072 ADP AMP Other reaction - Dephosphorylation Adenosine [7], [2]
MR004028 SAMP AMP Unclear Xanthine [6]
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Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000070 AMP ADP Other reaction - Phosphorylation Adenosine [7], [2]
MR004266 AMP ATP Unclear Methylthioadenosine [8]
MR011570 AMP Adenosine Unclear - Unclear Acadesine [5]
MR011571 AMP AMPK Unclear - Unclear Acadesine [5]
MR000071 AMP Adenosine Other reaction - Dephosphorylation Adenosine [7], [2]
MR004029 AMP ATP Unclear Xanthine [6]
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References
1 Condition-dependent adenosine monophosphate decomposition pathways in striated adductor muscle from Japanese scallop (Patinopecten yessoensis) J Food Sci. 2020 May;85(5):1462-1469. doi: 10.1111/1750-3841.15142.
2 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
3 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
4 Inosine in Biology and Disease
5 A multi-centre dose-escalation and pharmacokinetic study of diflomotecan in patients with advanced malignancy
6 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism
7 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
8 Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies
9 ATP and its metabolite adenosine cooperatively upregulate the antigen-presenting molecules on dendritic cells leading to IFN- production by T cells

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