Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004402)
Formula
SVG example
Hydrolyzationn
Reactant 1-(4-hydroxyphenyl)ethanone Product 3,4-Dihydroxybenzoic acid
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007185 Fendiline p-hydroxy-acetophenone Unclear Fendiline [1]
MR007187 Fendiline M4 p-hydroxy-acetophenone Unclear Fendiline [1]
MR007180 Hydroxyfendiline p-hydroxy-acetophenone Unclear Fendiline [1]
MR004399 2-(4-Hydroxyphenyl)acetic acid 1-(4-hydroxyphenyl)ethanone Unclear N-nonylphenol [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007181 p-hydroxy-acetophenone 3,3-diphenylpropylamine Unclear Fendiline [1]
MR007188 p-hydroxy-acetophenone Fendiline M11 Unclear Fendiline [1]
MR004400 1-(4-hydroxyphenyl)ethanone 4-Hydroxybenzoic acid Unclear N-nonylphenol [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012893 4-hydroxylaminobenzoate Protocatechuate Unclear Nitrobenzoate [3]
MR010922 Vanillic acid Protocatechuic acid Unclear - Unclear Isovanillin [4]
MR004360 4-hydroxylaminobenzoate Protocatechuate Unclear Nitrobenzaldehyde [3]
MR004588 DMPE 3,4-Dihydroxybenzoic acid Conjugation - Methylationn Phosethanolamine [5]
MR013910 Mebeverine Metabolite M1 Mebeverine Metabolite M2 Unclear - Unclear Mebeverine [6]
MR013912 Vanillic acid Mebeverine Metabolite M2 Unclear - Unclear Mebeverine [6]
MR004494 3'-4'-Dihydroxyphenylacetic acid 3,4-Dihydroxybenzoic acid Unclear VS-12343 [7]
MR003507 3,4-dihydroxyphenylacetic acid 3,4-Dihydroxybenzoic acid Unclear L-phenylalanine [8]
MR014114 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Oxidation - Alkyl-chain hydroxylation N-nonylphenol [2]
MR014115 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Unclear N-nonylphenol [2]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012894 Protocatechuate Alpha-hydroxy-gamma-carboxymuconic semialdehyde Other reaction - Ring cleavage reaction Nitrobenzoate [3]
MR010925 Protocatechuic acid Catechol Unclear - Unclear Isovanillin [4]
MR004361 Protocatechuate Nitrobenzaldehyde Metabolite M2 Other reaction - Ring cleavage reaction Nitrobenzaldehyde [3]
MR004495 3,4-Dihydroxybenzoic acid 3-Hydroxybenzoic acid Unclear VS-12343 [7]
References
1 Identification of fendiline metabolites in human urine
2 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement
3 Biodegradation of 4-nitrotoluene by Pseudomonas sp. strain 4NT
4 The metabolism of vanillin and isovanillin in the rat
5 Phospholipid N-Methyltransferases Produce Various Methylated Phosphatidylethanolamine Derivatives in Thermophilic Bacteria
6 Investigative implications of the instability and metabolism of mebeverine
7 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium
8 Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine Res Microbiol. 2007 Jul-Aug;158(6):506-11. doi: 10.1016/j.resmic.2007.04.008.

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