Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004400)
Formula
SVG example
Reactant 1-(4-hydroxyphenyl)ethanone Product 4-Hydroxybenzoic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007185 Fendiline p-hydroxy-acetophenone Unclear Fendiline [1]
MR007187 Fendiline M4 p-hydroxy-acetophenone Unclear Fendiline [1]
MR007180 Hydroxyfendiline p-hydroxy-acetophenone Unclear Fendiline [1]
MR004399 2-(4-Hydroxyphenyl)acetic acid 1-(4-hydroxyphenyl)ethanone Unclear N-nonylphenol [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007181 p-hydroxy-acetophenone 3,3-diphenylpropylamine Unclear Fendiline [1]
MR007188 p-hydroxy-acetophenone Fendiline M11 Unclear Fendiline [1]
MR004402 1-(4-hydroxyphenyl)ethanone 3,4-Dihydroxybenzoic acid Oxidation - Hydrolyzationn N-nonylphenol [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008831 Cetraxate PHBA Unclear - Unclear Cetraxate [3]
MR005873 Liquiritin metabolite M9 Liquiritin metabolite M11 Other reaction - Degradation Liquiritin [4]
MR006959 3-(4'-Hydroxyphenyl)acetic acid 4'-Hydroxybenzoic acid Unclear CCG-208408 [5]
MR013576 4'-hydroxyphenylacetic acid 4'-hydroxybenzoic acid Unclear Epigallocatechin gallate [6]
MR004502 4'-Hydroxyphenylacetic acid 4-Hydroxybenzoic acid Unclear VS-12343 [7]
MR004413 4-Hydroxy-4-(4-hydroxyphenyl) butanoic acid 4-Hydroxybenzoic acid Oxidation - Alkyl-chain hydroxylation N-nonylphenol [2]
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Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005874 Liquiritin metabolite M11 Liquiritin metabolite M13 Other reaction - Amino acid Liquiritin [4]
MR005875 Liquiritin metabolite M11 Liquiritin metabolite M14 Other reaction - Amino acid Liquiritin [4]
MR006960 4'-Hydroxybenzoic acid 4'-Hydroxyhippuric acid Unclear CCG-208408 [5]
MR013577 4'-hydroxybenzoic acid Hippuric acid Unclear Epigallocatechin gallate [6]
MR014114 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Oxidation - Alkyl-chain hydroxylation N-nonylphenol [2]
MR014115 4-Hydroxybenzoic acid 3,4-Dihydroxybenzoic acid Unclear N-nonylphenol [2]
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References
1 Identification of fendiline metabolites in human urine
2 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement
3 [Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent]
4 A comprehensive profiling and identification of liquiritin metabolites in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometer
5 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
6 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
7 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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