Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004485)
Formula Reactant Hesperetin Product 3-(3'-Hydroxy-4'-methoxyphenyl)-2-propionic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007030 Hesperetin Eriodictyol Oxidation - 4'-demethylation Hesperetin [1]
MR007031 Hesperetin Hesperetin 3p-O-Glucuronide Conjugation - Glucuronidation Hesperetin [2], [3]
MR007032 Hesperetin Hesperetin 7-O-glucuronide Conjugation - Glucuronidation Hesperetin [2], [3]
MR003858 Hesperetin Hesperetin-sulfo-O-glucuronide Unclear BRN-0183227 [4]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004507 3-(3'-Hydroxy-4'-methoxyphenyl)-2-propionic acid 3-(3'-Hydroxy-4'-methoxyphenyl)hydracrylic acid Unclear VS-12343 [5]
MR004486 3-(3'-Hydroxy-4'-methoxyphenyl)-2-propionic acid 3-(3'-Hydroxy-4'-methoxyphenyl)propionic acid Unclear VS-12343 [5]
MR004505 3-(3'-Hydroxy-4'-methoxyphenyl)-2-propionic acid Caffeic acid Unclear VS-12343 [5]
References
1 DrugBank(Pharmacology-Metabolism):Hesperetin
2 BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification
3 Molecular mechanism of hesperetin-7-O-glucuronide, the main circulating metabolite of hesperidin, involved in osteoblast differentiation
4 Stratification of Volunteers According to Flavanone Metabolite Excretion and Phase II Metabolism Profile after Single Doses of 'Pera' Orange and 'Moro' Blood Orange Juices
5 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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