Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004885)
Formula
SVG example
Hydrolyzationn
Reactant Nefazodone Product Hydroxynefazodone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004892 Nefazodone 3-[3-ethyl-5-oxo-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]propanal Oxidation - N-dealkylation Nefazodone [1]
MR004891 Nefazodone M-Chlorophenylpiperazine Unclear Nefazodone [2]
MR004888 Nefazodone Nefazodone Metabolite E Unclear Nefazodone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004886 Hydroxynefazodone M-Chlorophenylpiperazine Unclear Nefazodone [2]
MR004893 Hydroxynefazodone Triazoledione Unclear Nefazodone [2]
References
1 DrugBank(Pharmacology-Metabolism):Nefazodone
2 Clinical pharmacokinetics of nefazodone. Clin Pharmacokinet. 1997 Oct;33(4):260-75.

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