Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004982)
Formula
CYP3A4 ...
SVG example
Reactant Ticlopidine Product 2-Oxoticlopidine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004989 Ticlopidine 2-Chloroticlopidine Unclear Ticlopidine [1]
MR004993 Ticlopidine 7-Hydroxyticlopidine Unclear Ticlopidine [2]
MR004990 Ticlopidine Dehydrogenated ticlopidine Oxidation - Dehydrogenation Ticlopidine [1]
MR004992 Ticlopidine Di-Hydroxyticlopidine Unclear Ticlopidine [1]
MR004984 Ticlopidine Thienodihydropyridinium Oxidation - Dehydrogenation Ticlopidine [1]
MR004991 Ticlopidine Ticlopidine N-oxide Oxidation - N-oxidation Ticlopidine [1]
MR004987 Ticlopidine Ticlopidine S-oxide Unclear Ticlopidine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004983 2-Oxoticlopidine Active metabolite of Ticlopidine Unclear Ticlopidine [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 DrugBank(Pharmacology-Metabolism):Ticlopidine

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