Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004984)
Formula
MPO ...
SVG example
Dehydrogenation
Reactant Ticlopidine Product Thienodihydropyridinium
Reactant Info Product Info
Metabolic Enzyme Myeloperoxidase (MPO) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004989 Ticlopidine 2-Chloroticlopidine Unclear Ticlopidine [1]
MR004982 Ticlopidine 2-Oxoticlopidine Unclear Ticlopidine [1]
MR004993 Ticlopidine 7-Hydroxyticlopidine Unclear Ticlopidine [2]
MR004990 Ticlopidine Dehydrogenated ticlopidine Oxidation - Dehydrogenation Ticlopidine [1]
MR004992 Ticlopidine Di-Hydroxyticlopidine Unclear Ticlopidine [1]
MR004991 Ticlopidine Ticlopidine N-oxide Oxidation - N-oxidation Ticlopidine [1]
MR004987 Ticlopidine Ticlopidine S-oxide Unclear Ticlopidine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004986 Thienodihydropyridinium Thienopyridinium Unclear Ticlopidine [1]
MR004985 Thienodihydropyridinium Ticlopidine lactam analog (M8) Unclear Ticlopidine [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 DrugBank(Pharmacology-Metabolism):Ticlopidine

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