Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR005372)
Formula	CYP2B6 Hydrolyzationn
	Reactant	Lauric acid		Product	2-hydroxylauric acid
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 2B6 (CYP2B6)					DME Info
Metabolic Type	Oxidation - Hydrolyzationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005371	Lauric acid	11-hydroxylauric acid	Oxidation - Hydrolyzationn	Lauric acid	[1]
MR005368	Lauric acid	12-Hydroxydodecanoic Acid	Oxidation - Aliphatic hydroxylation	Lauric acid	[2], [1]

References
1	Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites
2	The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase

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