Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005371)
Formula
CYP2B6 ...
SVG example
Hydrolyzationn
Reactant Lauric acid Product 11-hydroxylauric acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Lauric acid omega-hydroxylase (CYP4A11) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005368 Lauric acid 12-Hydroxydodecanoic Acid Oxidation - Aliphatic hydroxylation Lauric acid [1], [2]
MR005372 Lauric acid 2-hydroxylauric acid Oxidation - Hydrolyzationn Lauric acid [2]
References
1 The omega-hydroxlyation of lauric acid: oxidation of 12-hydroxlauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase
2 Cytochrome P450 4A11 inhibition assays based on characterization of lauric acid metabolites

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