General Information of This Metabolic Reaction (MR) (ID: MR005911)
Formula
Reactant 2-deoxy-D-ribose 5-phosphate (DR5P) Product Acetaldehyde
Reactant Info Product Info
Metabolic Enzyme 2-deoxy-D-ribose 5-phosphate aldolase (DERA) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005909 2-deoxy-D-ribose 1-phosphate 2-deoxy-D-ribose 5-phosphate (DR5P) Unclear Thymidine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005910 2-deoxy-D-ribose 5-phosphate (DR5P) Glyceraldehyde 3-phosphate Unclear Thymidine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000453 BRN-1736748 Acetaldehyde Unclear BRN-1736748 [3], [4]
MR008004 Cefuroxime axetil Acetaldehyde Unclear - Unclear Cefuroxime axetil [5]
MR007449 Ethanol Acetaldehyde Oxidation - Oxidationn Ethanol [6]
MR004377 Nitrophenyl acetate Acetaldehyde Unclear Nitrophenyl acetate [7]
MR004209 PYR Acetaldehyde Unclear D-xylulose [8]
MR004160 4-Hydroxy-2-oxovaleric acid Acetaldehyde Unclear Aminophenol [9]
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References
1 Differential metabolism of 4-n- and 4-tert-octylphenols in perfused rat liver
2 Thymidine catabolism as a metabolic strategy for cancer survival. Cell Rep. 2017 May 16;19(7):1313-1321.
3 Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Nature. 2011 Apr 7;472(7341):57-63. doi: 10.1038/nature09922.
4 NORMAN Suspect List Exchange:Choline
5 DrugBank(Pharmacology-Metabolism):Cefuroxime axetil
6 Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System
7 Aldehyde dehydrogenase catalyses acetaldehyde formation from 4-nitrophenyl acetate and NADH
8 Effects of increased transaldolase activity on D-xylulose and D-glucose metabolism in Saccharomyces cerevisiae cell extracts
9 Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway

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