Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005978)
Formula Reactant GV-150526 Product p-Hydroxygavestinel
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005979 GV-150526 Gavestinel acyl glucuronid Conjugation - Glucuronidation GV-150526 [1]
MR005976 GV-150526 p-OH-gavestinel Oxidation - Aromatic hydroxylation GV-150526 [1]
MR005977 GV-150526 TGavestinel sulfate (M1) Unclear GV-150526 [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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