Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006071)
Formula
CYP3A4 ...
SVG example
Aliphatic hydroxylation
Reactant Z-4828 Product L-ifosfamide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 2A6 (CYP2A6) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Aliphatic hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006072 Z-4828 Ifosfamide Oxidation - N-dealkylation Z-4828 [1]
MR006073 Z-4828 L-cyclophosphamide Oxidation - N-dealkylation Z-4828 [1]
References
1 Metabolism and transport of oxazaphosphorines and the clinical implications Drug Metab Rev. 2005;37(4):611-703. doi: 10.1080/03602530500364023.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.