Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006089)
Formula
CYP1A1 ...
SVG example
Hydrolyzationn
Reactant CB-3304 Product Hydroxylated metabolite
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
DME Info
DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006091 CB-3304 CB-3304 Metabolite II Oxidation - Demethylation; cleavage CB-3304 [1]
MR006093 CB-3304 CB-3304 Metabolite VI Oxidation - Oxidationn CB-3304 [1]
MR006092 CB-3304 CB-3304 Metabolite X Oxidation - Bis-demethylation CB-3304 [1]
MR006094 CB-3304 Glucuronic acid conjugates Conjugation - Conjugation CB-3304 [1]
MR006088 CB-3304 Hydroxylated metabolite Oxidation - Hydrolyzationn CB-3304 [1]
MR006090 CB-3304 N-demethylated metabolite Oxidation - N-demethylation CB-3304 [1]
References
1 Metabolic map and bioactivation of the anti-tumour drug noscapine

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