Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006092)
Formula Reactant CB-3304 Product CB-3304 Metabolite X
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Bis-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006091 CB-3304 CB-3304 Metabolite II Oxidation - Demethylation; cleavage CB-3304 [1]
MR006093 CB-3304 CB-3304 Metabolite VI Oxidation - Oxidationn CB-3304 [1]
MR006094 CB-3304 Glucuronic acid conjugates Conjugation - Conjugation CB-3304 [1]
MR006088 CB-3304 Hydroxylated metabolite Oxidation - Hydrolyzationn CB-3304 [1]
MR006089 CB-3304 Hydroxylated metabolite Oxidation - Hydrolyzationn CB-3304 [1]
MR006090 CB-3304 N-demethylated metabolite Oxidation - N-demethylation CB-3304 [1]
References
1 Metabolic map and bioactivation of the anti-tumour drug noscapine

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