Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006094)
Formula Reactant CB-3304 Product Glucuronic acid conjugates
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006091 CB-3304 CB-3304 Metabolite II Oxidation - Demethylation; cleavage CB-3304 [1]
MR006093 CB-3304 CB-3304 Metabolite VI Oxidation - Oxidationn CB-3304 [1]
MR006092 CB-3304 CB-3304 Metabolite X Oxidation - Bis-demethylation CB-3304 [1]
MR006088 CB-3304 Hydroxylated metabolite Oxidation - Hydrolyzationn CB-3304 [1]
MR006089 CB-3304 Hydroxylated metabolite Oxidation - Hydrolyzationn CB-3304 [1]
MR006090 CB-3304 N-demethylated metabolite Oxidation - N-demethylation CB-3304 [1]
References
1 Metabolic map and bioactivation of the anti-tumour drug noscapine

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