Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006424)
Formula
CYP3A4 ...
SVG example
Oxidationn
Reactant R-1124 Product Netupitant N-Oxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006426 R-1124 Monohydroxy netupitant Oxidation - Hydrolyzationn R-1124 [1]
MR006425 R-1124 N\demethylated netupitant Oxidation - Demethylation R-1124 [1]
References
1 Netupitant PET imaging and ADME studies in humans

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