| General Information of This Metabolic Reaction (MR) (ID:
MR006592) |
| Formula |
|
| Reactant |
2-Oxoclopidogrel |
Product |
Active Metabolite of Clopidogrel |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 2B6 (CYP2B6)
|
DME Info
|
|
Cytochrome P450 3A4 (CYP3A4)
|
DME Info
|
|
Cytochrome P450 2C9 (CYP2C9)
|
DME Info
|
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
|
|
Metabolic Type
|
spontaneous
-
spontaneous
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Produce The Reactant of This MR
|
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
|
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