Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006591)
Formula
CYP2C19 ...
SVG example
Oxidationn
Reactant Clopidogrel bisulfate Product 2-Oxoclopidogrel
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006593 Clopidogrel bisulfate Clopidogrel carboxylic acid derivative Unclear Clopidogrel bisulfate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006592 2-Oxoclopidogrel Active Metabolite of Clopidogrel spontaneous - spontaneous Clopidogrel bisulfate [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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