Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006780)
Formula
CYP2C19 ...
SVG example
N-dealkylation
Reactant Tolterodine tartrate Product N-Dealkylated tolterodine
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006782 Tolterodine tartrate 5-Hydroxymethyl tolterodine Oxidation - Methyl-hydroxylation Tolterodine tartrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006781 N-Dealkylated tolterodine N-Dealkylated 5-hydroxymethyl tolterodine Unclear Tolterodine tartrate [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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