Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006830)
Formula
SVG example
Oxidationn; hydrolysis
Reactant Sonidegib phosphate Product Sonidegib metabolite M25
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Multi-steps Reaction - Oxidationn; hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006832 Sonidegib phosphate Sonidegib metabolite M16 Multi-steps Reaction - Oxidationn; hydrolysis Sonidegib phosphate [1]
MR006831 Sonidegib phosphate Sonidegib metabolite M48 Multi-steps Reaction - Oxidationn; hydrolysis Sonidegib phosphate [1]
References
1 Sonidegib: first global approval. Drugs. 2015 Sep;75(13):1559-66.

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