Details of the Metabolic Reaction (MR)
General Information of This Metabolic Reaction (MR) (ID: MR006867) | ||||||
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Formula |
CYP1A2
...
N-dealkylation
|
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Reactant | Enasidenib | Product | AGI-16903 | |||
Reactant Info | Product Info | |||||
Metabolic Enzyme | Cytochrome P450 1A2 (CYP1A2) | DME Info | ||||
Cytochrome P450 2B6 (CYP2B6) | DME Info | |||||
Cytochrome P450 2C8 (CYP2C8) | DME Info | |||||
Cytochrome P450 2C9 (CYP2C9) | DME Info | |||||
Mephenytoin 4-hydroxylase (CYP2C19) | DME Info | |||||
Metabolic Type | Oxidation - N-dealkylation | |||||
Other MR(s) Related to The Product of This MR | |||||||||||||||||||||||||||||
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Other MR(s) That Metabolize The Produtc of This MR | |||||||||||||||||||||||||||||
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References | ||||||
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1 | FDA:Enasidenib |
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