Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR006948)
Formula	CYP1A2 ... Desulfonization
	Reactant	Malathion		Product	Dimethyldithiophosphate
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 1A2 (CYP1A2)					DME Info
Metabolic Enzyme	Cytochrome P450 2B6 (CYP2B6)					DME Info
Metabolic Type	Other reaction - Desulfonization

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006943	Malathion	Malaoxon	Other reaction - Desulfonization	Malathion	[1]
MR006947	Malathion	Malathion monocarboxylic acid	Hydrolysis - Hydrolysis	Malathion	[1]

References
1	Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. Drug Metab Dispos. 2005 Mar;33(3):295-302.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.