Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008589)
Formula
SVG example
Reduction
Reactant Puerarin metabolite M50 Product Dihydrodaidzein
Reactant Info Product Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008588 Puerarin Puerarin metabolite M50 Hydrolysis - Hydrolysis Puerarin [1]
MR006104 CCRIS-1920 Metabolite M1 CCRIS-1920 Metabolite M2 Unclear CCRIS-1920 [2], [3]
MR006106 CCRIS-1920 Metabolite M3 CCRIS-1920 Metabolite M2 Unclear CCRIS-1920 [2], [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008591 Puerarin metabolite M50 Puerarin metabolite M63 Unclear - Unclear Puerarin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007067 Daidzein Dihydrodazein Reduction - Reduction Daidzein [4]
MR004169 Dihydrodaidzein Dihydrodaidzein Unclear Dihydrodaidzein [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007070 Dihydrodazein O-desmethylangolensin Unclear Daidzein [4]
MR007068 Dihydrodazein Tetrahydrodaidzein Unclear Daidzein [4]
References
1 Rapid profiling and identification of puerarin metabolites in rat urine and plasma after oral administration by UHPLC-LTQ-Orbitrap mass spectrometer
2 Cytochromes P450 and experimental models of drug metabolism. J Cell Mol Med. 2002 Apr-Jun;6(2):189-98.
3 Antiserotonergic properties of terguride in blood vessels, platelets, and valvular interstitial cells
4 Metabolism of Daidzein and Genistein by Gut Bacteria of the Class Coriobacteriia
5 R(-)-O-desmethylangolensin is the main enantiomeric form of daidzein metabolite produced by human in vitro and in vivo

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